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Correction to: Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy

The Original Article was published on 16 March 2018

Correction to: Transl Neurodegener 7, 6 (2018)

https://doi.org/10.1186/s40035-018-0111-2

Following the publication of the original article [1], it was noted that due to a typesetting error several lines are mistakenly added in the Fig. 1 and they should be deleted.

Fig. 1
figure 1

Surfen and oxalyl surfen are well tolerated by Tg [HuC::hTauP301L; DsRed] embryos. a Chemical structure of Surfen (1,3-bis(4-amino-2-methylquinolin-6-yl) urea), oxalyl surfen (N1,N2- bis(4-amino-2-methylquinolin-6-yl)oxalamide) and hemisurfen (1-(4-amino-2-methylquinolin-6- yl)urea). b Phenotypic analysis of 72 hpf wild-type (WT) and Tg [HuC::hTauP301L; DsRed] (hTauP301L) embryos incubated for 2 days in E3 medium containing 1% DMSO (hTauP301L + 1% DMSO), 80 mM LiCl (hTauP301L + LiCl), 3 μM surfen (hTauP301L + surfen), 2 μM oxalyl surfen (hTauP301L + oxalyl surfen) or 3 μM hemisurfen (hTauP301L + hemisurfen), showed that embryonic development is not impaired by the treatments. Magnification × 40. c Survival rate of 72 hpf wild-type (WT) and Tg [HuC::hTauP301L; DsRed] (hTauP301L) embryos incubated for 2 days in E3 medium containing 1% DMSO (hTauP301L + 1% DMSO), 80 mM LiCl (hTauP301L + LiCl), 3 μM surfen (hTauP301L + surfen), 2 μM oxalyl surfen (hTauP301L + oxalyl surfen), or 3 μM hemisurfen (hTauP301L + hemisurfen), demonstrated that embryonic mortality was not significantly increased by treatments (n = 250, P > 0.05, Student’s t test)

The correct figure has been included in this correction, and the original article has been corrected.

Reference

  1. Alavi Naini SM, et al. Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy. Transl Neurodegener. 2018;7:6. https://doi.org/10.1186/s40035-018-0111-2.

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Correspondence to Nadia Soussi-Yanicostas.

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Naini, S.M.A., Yanicostas, C., Hassan-Abdi, R. et al. Correction to: Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy. Transl Neurodegener 9, 45 (2020). https://doi.org/10.1186/s40035-020-00220-3

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