Translational Neurodegeneration

Featured articles

Ankit Verma, et al.

Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology

Winanto Ng & Shi-Yan Ng

Remodeling of astrocyte secretome in amyotrophic lateral sclerosis: uncovering novel targets to combat astrocyte-mediated toxicity

Articles

Employing nanoparticle tracking analysis of salivary neuronal exosomes for early detection of neurodegenerative diseases

Authors: Vaibhav Sharma, Fredrik Nikolajeff and Saroj Kumar

Content type: Review 7 February 2023
Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease

Authors: Luis Enrique Arroyo-García, Sara Bachiller, Rocío Ruiz, Antonio Boza-Serrano, Antonio Rodríguez-Moreno, Tomas Deierborg, Yuniesky Andrade-Talavera and André Fisahn

Content type: Research 6 February 2023
Links between COVID-19 and Parkinson’s disease/Alzheimer’s disease: reciprocal impacts, medical care strategies and underlying mechanisms

Authors: Pei Huang, Lin-Yuan Zhang, Yu-Yan Tan and Sheng-Di Chen

Content type: Review 30 January 2023
Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial

Authors: Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Halil Aziz Velioglu, Hong Yang, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu…

Content type: Research 26 January 2023
Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson’s disease dementia

Authors: Irene Frigerio, Max A. Laansma, Chen-Pei Lin, Emma J. M. Hermans, Maud M. A. Bouwman, John G. J. M. Bol, Yvon Galis-de Graaf, Dagmar H. Hepp, Annemieke J. M. Rozemuller, Frederik Barkhof, Wilma D. J. van de Berg and Laura E. Jonkman

Content type: Research 20 January 2023

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Recommendations for the diagnosis and treatment of paroxysmal kinesigenic dyskinesia: an expert consensus in China
Li Cao, Xiaojun Huang, Ning Wang, Zhiying Wu, Cheng Zhang, Weihong Gu, Shuyan Cong, Jianhua Ma, Ling Wei, Yanchun Deng, Qi Fang, Qi Niu, Jin Wang, Zhaoxia Wang, You Yin, Jinyong Tian, Shufen Tian, Hongyan Bi, Hong Jiang, Xiaorong Liu, Yang Lü, Meizhen Sun, Jianjun Wu, Erhe Xu, Tao Chen, Tao Chen, Xu Chen, Wei Li, Shujian Li, Qinghua Li, Xiaonan Song, Ying Tang, Ping Yang, Yun Yang, Min Zhang, Xiong Zhang, Yuhu Zhang, Ruxu Zhang, Yi Ouyang, Jintai Yu, Quanzhong Hu, Qing Ke, Yuanrong Yao, Zhe Zhao, Xiuhe Zhao, Guohua Zhao, Furu Liang, Nan Cheng, Jianhong Han, Rong Peng, Shengdi Chen & Beisha Tang
Review | 16 February 2021

COVID-19 and Alzheimer’s disease: how one crisis worsens the other
Xiaohuan Xia, Yi Wang & Jialin Zheng
Review | 30 April 2021

The Gold Coast criteria increases the diagnostic sensitivity for amyotrophic lateral sclerosis in a Chinese population
Dongchao Shen, Xunzhe Yang, Yanying Wang, Di He, Xiaohan Sun, Zhengyi Cai, Jinyue Li, Mingsheng Liu & Liying Cui
Research | 09 August 2021

Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review
Tapan Behl, Gagandeep Kaur, Ovidiu Fratila, Camelia Buhas, Claudia Teodora Judea-Pusta, Nicoleta Negrut, Cristiana Bustea & Simona Bungau
Review | 15 January 2021

Immunotherapy for Alzheimer’s disease: targeting β-amyloid and beyond
Chenghuan Song, Jiyun Shi, Pingao Zhang, Yongfang Zhang, Jianrong Xu, Lanxue Zhao, Rui Zhang, Hao Wang & Hongzhuan Chen
Review | 18 March 2022

2022

Thematic series
Recent progresses on early diagnosis of Parkinson’s disease and related disorders
Edited by Anthony E. Lang

Thematic series
Clearance of neurotoxic proteins in proteinopathies: from clearance pathways to therapeutic targets
Edited by Shengdi Chen

Thematic series
PD progresses in recent 10 years: from hypothesis to therapeutic targets
Edited by Shengdi Chen

Thematic series
AD progresses in recent 10 years: from hypothesis to therapeutic targets
Edited by Weihong Song

2021

Thematic series
MicroRNAs and neurodegenerative diseases
Edited by Zixu Mao

Thematic series
Mitochondria dysfunctions and neurodegenerative diseases
Edited by Xiongwei Zhu

2015

Thematic series
Update on Amyotrophic lateral sclerosis: from genetic and mitochondria perspective
Edited by Shengdi Chen and Jialin Zheng

Thematic series
Stem cell-based therapy for Alzheimer’s disease: the current situation and future prospects

Thematic series
Pharmacological treatment for early and advanced stages of Parkinson’s disease: current and future strategies
Edited by Shengdi Chen and Jialin Zheng

2014

Cross journal collection
Reviewer acknowledgements 2013

Editor-in-Chief

Shengdi Chen, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China

Aims and Scope

Translational Neurodegeneration is an open access, peer-reviewed journal that covers research, therapeutics and education for all aspects of neurodegenerative diseases. By offering a high-visibility forum for new insights and discussions, Translational Neurodegeneration creates a novel interface between the fields of basic, translational, and clinical research. It includes Parkinson's disease and movement disorders, Alzheimer's disease and other dementias, motor neuron disease and other neurodegenerative diseases.