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Translational Neurodegeneration: 10th Anniversary

1652107005Inaugurated in 2012 under the editorship and leadership of Dr. Shengdi Chen, the mission of Translational Neurodegeneration (TN) is to promote and foster rapid conversion of basic science research to clinical applications by offering a high-visibility forum for groundbreaking translational research in neurodegenerative diseases and to ultimately benefit not only patients but also societies. 

In this Editorial, the editors have reviewed the splendid progresses in the journal during the past ten years, and discussed the goals to achieve in the next ten years. 

10th Anniversary Video

Click here to enlarge the infographic


Best Paper Award for 10th Anniversary of Translational Neurodegeneration

Article title

Authors (#corresponding authors)

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

Qinqin Wang, Yingjun Liu & Jiawei Zhou#

Protein misfolding in neurodegenerative diseases: implications and strategies

Patrick Sweeney#, Hyunsun Park, Marc Baumann, John Dunlop, Judith Frydman, Ron Kopito, Alexander McCampbell, Gabrielle Leblanc, Anjli Venkateswaran, Antti Nurmi & Robert Hodgson

Imaging biomarkers in Parkinson’s disease and Parkinsonian syndromes: current and emerging concepts

Usman Saeed, Jordana Compagnone, Richard I. Aviv, Antonio P. Strafella, Sandra E. Black, Anthony E. Lang & Mario Masellis#

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration

Yong-Bo Hu, Eric B Dammer, Ru-Jing Ren# & Gang Wang#

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Panchanan Maiti#, Jayeeta Manna & Gary L. Dunbar#

Alzheimer’s disease hypothesis and related therapies

Xiaoguang Du, Xinyi Wang & Meiyu Geng#

The changing phenotype of microglia from homeostasis to disease

Xiao-Guang Luo & Sheng-Di Chen#

Mitochondrial dysfunction in Parkinson’s disease

Qingsong Hu & Guanghui Wang#

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

Hyuk Sung Kwon & Seong-Ho Koh#

Role of early life exposure and environment on neurodegeneration: implications on brain disorders

Shweta Modgil, Debomoy K Lahiri, Vijay L Sharma & Akshay Anand#

Article title

Authors (#corresponding authors)

miRNA expression profiles in cerebrospinal fluid and blood of patients with Alzheimer’s disease and other types of dementia – an exploratory study

Sofie Sølvsten Sørensen, Ann-Britt Nygaard & Thomas Christensen#

Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

Wenyan Zou, Tinglin Pu, Weixi Feng, Ming Lu, Ying Zheng, Renhong Du, Ming Xiao# & Gang Hu#

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome

Antonella Tramutola, Chiara Lanzillotta, Eugenio Barone, Andrea Arena, Ilaria Zuliani, Luciana Mosca, Carla Blarzino, D. Allan Butterfield, Marzia Perluigi# & Fabio Di Domenico#

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson’s disease through suppressing mitochondria dysfunction

Jing Pan, Hui Li, Jian-Fang Ma, Yu-Yan Tan, Qin Xiao, Jian-Qing Ding# & Sheng-Di Chen#

Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts

Nady Braidy, Wei-Ping Gai, Ying Hua Xu, Perminder Sachdev, Gilles J Guillemin, Xing-Mai Jiang, J William O Ballard, Martin P Horan, Zhi Ming Fang, Beng H Chong & Daniel Kam Yin Chan#

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy

Chiara Maria Giulia De Luca, Antonio Emanuele Elia, Sara Maria Portaleone, Federico Angelo Cazzaniga, Martina Rossi, Edoardo Bistaffa, Elena De Cecco, Joanna Narkiewicz, Giulia Salzano, Olga Carletta, Luigi Romito, Grazia Devigili, Paola Soliveri, Pietro Tiraboschi, Giuseppe Legname, Fabrizio Tagliavini, Roberto Eleopra, Giorgio Giaccone & Fabio Moda#

Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study

Toni L Pitcher#, Tracy R Melzer, Michael R MacAskill, Charlotte F Graham, Leslie Livingston, Ross J Keenan, Richard Watts, John C Dalrymple-Alford & Tim J Anderson

Erythrocytic α-Synuclein as a potential biomarker for Parkinson’s disease

Chen Tian, Genliang Liu, Liyan Gao, David Soltys, Catherine Pan, Tessandra Stewart, Min Shi, Zhiying Xie, Na Liu, Tao Feng# & Jing Zhang#

Cerebrospinal fluid phosphorylated tau, visinin-like protein-1, and chitinase-3-like protein 1 in mild cognitive impairment and Alzheimer’s disease

Hua Zhang, Kok Pin Ng, Joseph Therriault, Min Su Kang, Tharick A. Pascoal, Pedro Rosa-Neto, Serge Gauthier# & the Alzheimer’s Disease Neuroimaging Initiative

Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer’s disease and dementia with Lewy bodies

Ana Gámez-Valero, Jaume Campdelacreu, Dolores Vilas, Lourdes Ispierto, Ramón Reñé, Ramiro Álvarez, M. Pilar Armengol, Francesc E. Borràs# & Katrin Beyer#

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