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Fig. 9 | Translational Neurodegeneration

Fig. 9

From: Supplementation with high-GABA-producing Lactobacillus plantarum L5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA

Fig. 9

The gut microbiota in patients with ET has a lower GABA-producing capacity and is able to induce ET-like behavioral abnormalities in mice (a). Administration of Lactobacillus plantarum L5 alleviates ET by reshaping the gut microbial composition, increasing the GABA-producing capacity of the mucosa-associated microbiota, and elevating the concentration of GABA in the cerebellum (b)

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