Fig. 5

L. plantarum L5 shaped the gut microbial composition in ET mice. a Shannon’s diversity index at the generic level. b Principal coordinate analysis (PCoA) of microbiota composition at the generic level. c Bar plot of relative abundances of the top ten differential genera between ET mice treated with L5 or normal saline and the results of the Wilcoxon rank-sum test. d Heatmap of the correlations between the relative abundances of gut microbes at the generic level and ET severity parameters. L5, L. plantarum L5; NS, normal saline. Box plots indicate the median and interquartile range. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001