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Fig. 4 | Translational Neurodegeneration

Fig. 4

From: Supplementation with high-GABA-producing Lactobacillus plantarum L5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA

Fig. 4

L. plantarum L5 attenuated the central nervous system inflammation in ET mice. a, b Concentrations of IL-1β, IL-6, and TNF-α in the cerebellum (a) and cerebrum (b) of mice with harmaline-induced ET treated with L5 or normal saline. c Heatmap showing correlations between the levels of inflammatory cytokines in the central nervous system with severity parameters of ET (tremor intensity, grip strength, total distance moved, and active duration). Data are presented as mean ± standard deviation. *P < 0.05; **P < 0.01; ***P < 0.001

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