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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Supplementation with high-GABA-producing Lactobacillus plantarum L5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA

Fig. 3

High-GABA-producing L. plantarum strain L5 ameliorated the harmaline-induced ET symptoms in mice. a Study design involving mice treated with L5 or normal saline daily for four weeks, followed by harmaline treatment to induce ET. b Quantitative analysis of the tremor intensity score. c Representative activity trajectories. d Total distance covered in 5 min. e Grip strength. f Onset time. g Active duration in 5 min. h, i Quantitative analysis of pole test (h) and rotarod test data (i). L5, L. plantarum L5; NS, normal saline. Data are presented as the mean ± standard deviation. *P < 0.05; **P < 0.01

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