Fig. 1
From: Oligodendrocyte progenitor cells in Alzheimer’s disease: from physiology to pathology
The process of oligodendrocyte progenitor cell (OPC) myelination varies during different stages. a During development, OPCs generated from neural stem cells rapidly form myelin sheaths, and a fraction of OPCs will be reserved in the stem cell pool. b In adulthood, upon demyelination, OPCs residing in the stem cell pool are swiftly recruited to the site of injury along the vasculature, where they proliferate and differentiate to initiate remyelination