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Fig. 6 | Translational Neurodegeneration

Fig. 6

From: Intranasal administration of induced pluripotent stem cell-derived cortical neural stem cell-secretome as a treatment option for Alzheimer’s disease

Fig. 6

Anti-inflammatory effects of CNSC-SE on hyperexcitable microglia. a Confocal images of Iba-1 immunostaining in the whole brains of 5×FAD (AD model mice) and CNSC-SE-treated 5×FAD mice. b Representative images of Aβ (6E10) plaques and microglia (Iba-1) co-staining in the cortex of 5×FAD mice and CNSC-SE-treated 5×FAD mice. c Quantification of Iba-1-positive microglia and internalized Aβ using the Image J software. Scale bars, 20 μm

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Translational Neurodegeneration

ISSN: 2047-9158

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