Fig. 1From: NLRP3 inflammasome in cognitive impairment and pharmacological properties of its inhibitorsSchematic diagram of the relationships between NLRP3 and mitochondrial autophagy. On the one hand, damaged mitochondria can produce ROS and DAMPs, which can activate the NLRP3 inflammasome [65]. On the other hand, mitochondrion autophagy negatively regulates the activation of the NLRP3 inflammasome by removing activators of the inflammasome [57]Back to article page