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Table 4 The role of extracellular vesicles in Huntington’s disease

From: Research progress on the role of extracellular vesicles in neurodegenerative diseases

Source of EVs

Content with biomarker potential

Mouse and cell models for mechanistic studies

Downstream pathway or molecule

References

SH-SY5Y cells

mHTT

NA

NA

[166]

CAD cells

CSPα

CSPα knock-out mice

SOD-1

[170]

HEK-293 cells

miR-124

R6/2 HD mice

RE1-Silencing Transcription Factor

[171]

  1. NA No accessible data in the study; HEK-293 cells Human embryonic kidney 293 cells; CSPα cysteine string protein α