Impact of seed amplification assay and surface-enhanced Raman spectroscopy combined approach on the clinical diagnosis of Alzheimer’s disease

Table 2 Performance of the classifier in the test set for both AD patients versus ONC patients and AD versus HyC

Dataset	AUROC	Accuracy	Sensitivity	Specificity
AD vs ONC	0.85 (0.16)	0.84 (0.12)	0.88 (0.13)	0.77 (0.22)
AD vs HyC	0.84 (0.20)	0.85 (0.13)	0.89 (0.13)	0.81 (0.20)

The HyC group was a subgroup of ONC. Data are mean (standard deviation) over the iterations of the 5-fold cross-validation. AD: Alzheimer’s disease; ONC: other neurodegenerative conditions; AUROC: area under the receiver operating characteristic curve; HyC: patients with normal pressure hydrocephalus

ISSN: 2047-9158