Fig. 4
From: Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints
Associations of plasma and PET imaging ATN biomarkers with neuropsychological tests. Partial correction analysis after adjustment for age and sex was applied to evaluate the associations between plasma and PET imaging ATN biomarkers and the results of neuropsychological tests in the entire cohort (a) as well as in Aβ+ (b) and Aβ− (c) subjects. Unadjusted P values are presented with asterisks (***, P < 0.001; **, P < 0.01; *, P < 0.05) whereas those that remained significant after correcting for multiple comparisons (Bonferroni’s correction, Pc < 0.05) are marked with solid frames. The results of neuropsychological testing on different cognitive domains were transformed to Z-scores. The color bars denote partial correlation coefficients (r). MMSE Mini-Mental State Examination, MOCA Montreal Cognitive Assessment, FAQ Functional Activities Questionnaire, PET Positron emission tomography, SUVR Standardized uptake value ratio, MTL Medial temporal lobe; NEO-T Temporal neocortex, metaROI Meta-analytically derived region of interest, t-tau total tau, NfL Neurofilament light chain