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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints

Fig. 2

Agreement between plasma p-tau181 levels and PET imaging ATN biomarkers for predicting the Aβ status. The concordance rates are based on the established thresholds for the biomarkers. The sums of negative and positive concordance rates are presented. Color bars summarize the concordance rates between plasma p-tau181 level and different PET imaging ATN biomarkers in the entire cohort (upper row) as well as Aβ+ subjects (intermediate row) and Aβ− subjects (lower row). Negative (− −) and positive (+ +) agreement are denoted in green and orange, respectively. Disagreement is reported in magenta (+ −; positive SUVR value on PET and negative p-tau181 level) or in blue (− + ; negative SUVR value on PET and positive p-tau181 level). A/T/N, Amyloid/Tau/Neurodegeneration, SUVR Standardized uptake value ratio, MTL Medial temporal lobe, NEO-T Temporal neocortex; metaROI, meta-analytically derived region of interest; p-tau181, tau phosphorylated at threonine 181

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