Fig. 1
From: Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints
Reciprocal associations between plasma and PET imaging ATN biomarkers: voxel-wise analysis. Voxel-wise regression analysis of standardized uptake value ratios from 18F-florbetapir PET for A (a), 18F-Florzolotau PET for T (b), and 18F-FDG PET for N (c) in relation to plasma ATN biomarkers (Aβ42/Aβ40 ratio, p-tau181, t-tau, NfL) adjusted for age, sex, and the interval from PET imaging to blood collection; calculations were performed in the entire cohort, as well as in Aβ+ and Aβ− subjects. The statistical threshold was set at a family wise error (FWE)-corrected P value < 0.05. The positive correlations are displayed in orange-red color scale. The negative correlations are displayed in cyan-blue color scale. PET Positron emission tomography, t-tau, total tau, NfL Neurofilament light chain, FWE Family-wise error