Table 1 Donor’s characteristics
Control | PD | PDD/DLB | |
|---|---|---|---|
N | 18 | 9 | 12 (7 PDD, 5 DLB) |
Sex M/F (%M) | 8/10 (44%) | 6/3 (67%) | 7/5 (58%) |
Age at diagnosis (years), mean ± SD | – | 62 ± 7 | 68 ± 12 |
Disease duration (years), mean ± SD | – | 18 ± 5 | 11 ± 6ϮϮ |
Age at death (years), mean ± SD | 73 ± 8 | 80 ± 9 | 78 ± 9 |
Post-mortem delay (minutes), mean ± SD | 524 ± 110 | 469 ± 153 | 443 ± 107 |
Radiologic characteristics | |||
NBV (L) mean ± SD | 1.46 ± 0.07 | 1.43 ± 0.08 | 1.38 ± 0.07* |
NGMV (L) mean ± SD | 0.74 ± 0.05 | 0.72 ± 0.04 | 0.70 ± 0.04* |
NWMV (L) mean ± SD | 0.72 ± 0.03 | 0.72 ± 0.05 | 0.68 ± 0.04 |
Pathological characteristics | |||
Braak LB stage [55] N | 18 | 9*** | 12*** |
0/1/2/3/4/5/6 | 15/2/1/0/0/0/0 | 0/0/0/0/1/1/7 | 0/0/0/0/0/0/12 |
ABC score [56] N | 18 | 9 | 12 |
A 0/1/2/3 | 4/13/1/0 | 1/6/2/0 | 0/3/5/4** |
B 0/1/2/3 | 3/15/0/0 | 0/7/2/0 | 0/5/7/0** |
C 0/1/2/3 | 18/0/0/0 | 7/2/0/0 | 5/1/6/0** |
Thal phase [52] N | 18 | 9 | 12** |
0/1/2/3/4/5 | 4/8/5/1/0/0 | 1/3/3/2/0/0 | 0/2/1/5/3/1 |
Braak NFT stage [51] N | 18 | 9 | 12*** |
0/1/2/3/4/5/6 | 3/11/4/0/0/0/0 | 0/2/5/1/1/0/0 | 0/0/5/2/5/0/0 |
CAA type [57] N | 18 | 9 | 12 |
No CAA/type 1/ type 2 | 14/1/3 | 9/0/0 | 5/4/3 |