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Table 3 EC50 of antibody binding to rTfR or Aβ in direct ELISA

From: ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein

ELISA target

OX265

OX2676

Bapi

OX265-F(ab′)2-Bapi

OX2676-F(ab′)2-Bapi

Unlabelled

[125I]-labelled

Unlabelled

[125I]-labelled

rTfR

0.62

2.54

–

1.28

1.36

Undetectable

Undetectable

Aβ

–

–

0.03

0.05

0.05

0.08

0.34

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Translational Neurodegeneration

ISSN: 2047-9158

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