Fig. 3
From: Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease
Melatonin decreases tau phosphorylation in 13-month-old hTau mice. Immunofluorescence using an AT8 (epitopes for pS202/T205-Tau) (a) or anti-pT231 Tau (b) antibody was performed on paraffin-embedded cortical and hippocampal sections from WT (n = 8), saline-treated hTau (hTau + SA) (n = 5) and melatonin-treated hTau (hTau + MT) (n = 5) mice. Scale bars, 50 μm. Data are presented as the means ± standard errors (*P < 0.05, **P < 0.01, ***P < 0.001)