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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential

Fig. 1

Rodent and human BDNF gene structures. a Rodent Bdnf gene structure. b Human BDNF gene structure. Exons are shown as boxes and introns are shown as lines. In both structures, the same color indicates that human exons and rodent exons are homologous. The different exons (Vh and VIIIh) are shown as red box and pink box, respectively. In exon II, there are three transcript variants which are marked as A, B and C. In human BDNF exon IX, there are four different regions that are marked as a, b, c and d. The numbers above the introns and below the exons indicate their base pair sizes. The red arrows indicate the positions in which the transcription starts. ATG represents the sites of the translational start and TAG marks the location of stop codons

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