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Fig. 5 | Translational Neurodegeneration

Fig. 5

From: Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials

Fig. 5

NfL Model Transferability. The absolute deviations of the predicted ALSFRS-R slope using the NfL model from the observed ALSFRS-R slope are plotted against the predicted value (a) and the time between disease onset and NfL measurement (b). The NfL model predictions use coefficients from the developing cohort, as shown in Fig. 3. Triangular arrowheads indicate points outside the coordinate system, and points inside the green box represent predictions within 0.5 pt/m from the measured value. Colored lines in panel b show local regression

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