Fig. 2

Coronal and sagittal SPECT images and coronal ex vivo autoradiography (AR) images of representative tg-ArcSwe mice from day 3 to day 27 after injection of [¹²⁵I]RmAb158-scFv8D3 (a) (3 days: n = 4; 6 days: n = 4; 14 days: n = 3; 27 days: n = 5) or [¹²⁵I]RmAb158 (b) (3 days: n = 2; 6 days: n = 3; 14 days: n = 4; 27 days: n = 3). c, d AR of WT mice injected with [¹²⁵I]RmAb158-scFv8D3 (n = 1) (c) and [¹²⁵I]RmAb158 (n = 1) (d) on day 3 post injection. Images were decay-corrected and normalized to injected dose