Fig. 3

Target GCH1 regions with associative results and linkage disequilibrium. The top scatter plot shows the association analysis of P-values in the WGS cohort and degree of linkage disequilibrium (LD) with the lead single variant. The solid line marks the Bonferroni-corrected significance threshold and the dashed line marks the suggestive significance threshold of P < 0.05. In the target regions, gray color depicts the range of eQTLs, blue color depicts regulatory regions, and orange shows transcript region. The bottom plot demonstrates the LD blocks of target regions. *Three variants were not included in the figure because these were in the distal region of present targets and were not associated with PD.