Table 1 Age-associated retinal functional changes in APP/PS1 and WT mice*

 3

− 157.6 ± 38

217.5 ± 40a,c

123 ± 22a,b,d

173.5 ± 29b,d

 6

−136.7 ± 28

174.7 ± 35

77.1 ± 15a,b

119.3 ± 29b

 9

− 118.9 ± 38

146.2 ± 43a

66.5 ± 8b

92.9 ± 30d

 12

−116 ± 57

107.7 ± 37c

49.8 ± 12d,b

98.6 ± 24d

p-value (ANOVA)

0.1

< 0.001

< 0.0001

< 0.0001

 3

− 144.5 ± 45

174.6 ± 31a

112.9 ± 9b,c

117.1 ± 29b,c

 6

−144.3 ± 30

155 ± 21a

99.4 ± 18 a

109.1 ± 23a,b

 9

− 135.4 ± 29

137.6 ± 34a

83.4 ± 16b,a

80.7 ± 24b,a

 12

− 123.2 ± 33

118 ± 31c

74.8 ± 11c,a

68.5 ± 18c,b

p-value (ANOVA)

0.2

< 0.001

< 0.001

< 0.001