Skip to main content

Advertisement

Table 3 Patients with dementia due to AD stratified according to the A/T/N

From: Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET

A/T/(N) system Biomarker group AD biomarker concordance n
A+/T+/N+ (n = 21) A+ Concordance between amyloid PET and CSF-Aβ42 10
Either amyloid PET or CSF-Aβ42 positivity 3
Only CSF-Aβ42 available 8
N+ Concordance between FDG PET, CSF-tTau and atrophy (cMRI) 18
Concordance between atrophy (cMRI) and either FDG-PET or CSF-tTau positivity 3
A+/T−/N+ (n = 11) A+ Concordance between amyloid PET and CSF-Aβ42 5
Either amyloid PET or CSF-Aβ42 positivity 2
Only CSF-Aβ42 available 4
N+ Concordance between FDG PET, CSF-tTau and atrophy (cMRI) 6
Concordance between atrophy (cMRI) and either FDG-PET or CSF-tTau positivity 3
  1. A+ Amyloid pathology, T Tau pathology, N Neuronal injury, PET Position emission tomography, CSF Cerebral spinal fluid, cMRI cranial magnetic resonance imaging, FDG-PET [18F]fluorodeoxyglucose-position emission tomography, amyloid β