| | |
AD-D
|
AD-noD
|
p
|
All
|
|---|
| | |
(n = 171)
|
(n = 86)
|
(N = 257)
|
|---|
|
Sexa
|
(M/F)
|
55/116
|
27/59
|
0.999
|
82/175
|
|
(Ratio)
|
0.47
|
0.46
| |
0.47
|
|
Age
|
(Years)
|
79.84 ± 6.80
|
80.97 ± 6.22
|
0.254
|
80.21 ± 6.62
|
|
Body mass index
|
(Kg/m2)
|
26.81 ± 5.89
|
25.15 ± 6.03
|
0.106
|
26.30 ± 5.95
|
|
Educational level
|
(Years)
|
4.25 ± 3.83
|
4.26 ± 3.49
|
0.798
|
4.26 ± 3.72
|
|
Social support networkb
|
Living alone
|
34 (19.88%)
|
2 (2.33%)
|
0.000
|
36 (14.01%)
|
|
Living with family
|
112 (65.50%)
|
82 (95.35%)
| |
194 (75.49%)
|
|
Institutionalized
|
25 (14.62%)
|
2 (2.33%)
| |
27 (10.51%)
|
|
Concomitant treatments
|
(No. of drugs)
|
6.60 ± 3.07
|
5.08 ± 3.12
|
0.026
|
6.15 ± 3.14
|
|
Clinical characteristics
|
|
MNA
| |
18.81 ± 5.77
|
20.98 ± 5.64
|
0.011
|
19.48 ± 5.81
|
|
ADL
| |
3.27 ± 1.98
|
3.89 ± 1.86
|
0.025
|
3.47 ± 1.96
|
|
IADL
| |
2.05 ± 2.39
|
2.87 ± 2.81
|
0.037
|
2.31 ± 2.55
|
|
CIRS-CI
| |
2.74 ± 1.62
|
2.73 ± 1.74
|
0.870
|
2.74 ± 1.66
|
|
ESS
| |
14.50 ± 3.29
|
15.80 ± 3.29
|
0.008
|
14.89 ± 3.33
|
|
SPMSQ
| |
5.29 ± 1.93
|
4.75 ± 1.87
|
0.014
|
5.11 ± 1.93
|
|
Age at onsetc
|
(Years)
|
78.03 ± 6.68
|
78.84 ± 6.16
|
0.143
|
78.02 ± 6.53
|
|
Disease duration
|
(Years)
|
2.23 ± 0.88
|
2.09 ± 0.94
|
0.226
|
2.18 ± 0 90
|
|
MMSE
| |
16.81 ± 5.92
|
18.33 ± 5.64
|
0.017
|
17.32 ± 5.86
|
|
NPI
| |
35.57 ± 20.94
|
22.72 ± 17.04
|
0.000
|
31.14 ± 20.57
|
|
NPI-Distress
| |
15.71 ± 8.08
|
9.32 ± 5.96
|
0.000
|
13.58 ± 8.02
|
|
Delusion symptom duration
|
(Years)
|
2.99 ± 0.79
|
–
|
–
|
1.39 ± 1.18
|
|
Delusion symptom severity
| |
6.38 ± 3.25
|
–
|
–
|
4.27 ± 4.01
|
- Values of continuous variables are presented as mean ± standard deviation (SD)
- aFisher’s Exact Test for Count Data; bPearson’s Chi-squared test; cWelch Two Sample t-test. All the other variables were compared by the Wilcoxon rank sum test with continuity correction
- AD-D AD patients with delusions, AD-noD AD patients without delusions, MNA Mini Nutritional Assessment, ADL Activities of Daily Living, IADL Instrumental Activities of Daily Living, CIRS-CI Cumulative Illness Rating Scale Comorbidity Index, ESS Exton-Smith Scale, SPMSQ Short Portable Mental Status Questionnaire, MMSE Mini-Mental State Examination, NPI Neuropsychiatric Inventory
