Skip to main content
Fig. 6 | Translational Neurodegeneration

Fig. 6

From: Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation

Fig. 6

Preferential overexpression of CRYAB in astrocytes promotes protein aggregation of a-synuclein in SNCAA30P mutant mouse brain. a Expression levels of RIPA-soluble and RIPA-insoluble protein fractions extracted from the ventral midbrain (VM) in CRYABTg / SNCAA30P Tg+. The graph shows a statistical analysis of the conversion of insoluble to soluble α-synuclein in the tissue. Data are presented as mean ± SEM, n = 5. b Expression levels of RIPA-soluble and RIPA-insoluble protein fractions extracted from the striatum in CRYABTg / SNCAA30P Tg+. The graph shows a statistical analysis of the conversion of insoluble to soluble α-synuclein in the tissue. Data are presented as mean ± SEM, n = 5

Back to article page