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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: GM604 regulates developmental neurogenesis pathways and the expression of genes associated with amyotrophic lateral sclerosis

Fig. 2

Top-ranked genes with expression most strongly altered by GM6. (a, c, e) GM6-increased genes. Heatmaps show genes most strongly increased by GM6 at the (a) 6 h, (c) 24 h and (e) 48 h time points. (b, d, f) GM6-decreased genes. Heatmaps show genes most strongly decreased by GM6 at the (b) 6 h, (d) 24 h and (f) 48 h time points. (g) KIAA1522 expression. (h) Synaptotagmin like 5 (SYTL5) expression. (i) Coronin 6 (CORO6) expression. (j) Regulator of G protein signaling 4 (RGS4) expression. (k) Transmembrane protein 255A (TMEM255A) expression. (l) TNF receptor superfamily member 19 (TNFRSF19) expression. In (g) – (l), letters shown for each bar indicate results from post hoc treatment comparisons (Fisher’s least significant difference), where treatments not sharing the same letter differ significantly (P < 0.05)

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