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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo

Fig. 2

6-Hydroxydopamine activates immunoproteasomes in DA neurons in vivo. The expression of β5, β5i (a, b), TAP1 and Bip (c, d) in the SN of the 6-OHDA hemilesioned rat model. e The colocalization of β5i on TH neurons in the SN at 1 day after 6-OHDA treatment. Scale bar = 100 μm. * P < 0.05, compared with control. N, normal group without treatment. C, control side of the brain. L, lesioned side of the brain. Data are presented as the mean ± SD; n = 4 experiments; one-way ANOVA and post hoc SNK t-test

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