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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo

Fig. 1

6-Hydroxydopamine activates immunoproteasomes in DA neurons in a dose-dependent manner. a The expression of β5 and β5i in SN4741 cells under 6-OHDA treatment by in-cell western assay and (b) the fluorescence intensity in each group after normalization to that in the normal group are shown. c-h The expression of β5, β5i, TAP1, Bip, Bax, Bcl-2, Caspase-3 and Cleaved Caspase-3 in SN4741 cells after different concentrations of 6-OHDA treatment for 24 h. Data are presented as the mean ± SD; n = 4 experiments; two-way ANOVA and post hoc SNK t-test

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Translational Neurodegeneration

ISSN: 2047-9158

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