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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: AGE-induced neuronal cell death is enhanced in G2019S LRRK2 mutation with increased RAGE expression

Fig. 2

G2019S LRRK2 neurons show increased cell death against AGEs. a. Representative images show 0.1 μg/μl or 0.15 μg/μl AGE-treated neurons. Neuron cultures were derived from striatum of WT LRRK2 or G2019S LRRK2 transgenic pups. After 24 h, neurons (15 DIV) were immunostained with MAP2 (green) antibody. Scale bar, 40 μm. b. Bar graph shows quantification of survived cells in (a). Data are presented as mean ± SD for three independent experiments. ***P < 0.001

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