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Fig. 16 | Translational Neurodegeneration

Fig. 16

From: Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Fig. 16

Different steps of generation of DA-neurons from stem cells for treating PD. Stem cells are obtained from different sources and converted to induced pluoripotent stem cells (iPSCs) using growth factors, such as Fgf2, Shh, Klf4 and c-Myc. The iPSCs is then converted to induced neuronal stem cells (iNSCs). These cells are then converted to DA-neurons by treating different growth factors. These DA-neurons are then injected to the brain of mouse model of PD to supply DA, which ultimately leads to the recovery of motor and cognitive deficits

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Translational Neurodegeneration

ISSN: 2047-9158

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