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Table 1 Progression of AD and usual symptoms

From: Clinical management and associated costs for moderate and severe Alzheimer’s disease in urban China: a Delphi panel study

Diagnosis 3–5 years after diagnosis 6–9 years after diagnosis ≥10 years after diagnosis
30–40 % patients experience mild cognitive impairments and/or personality changes for 1–2 years before visiting the hospital. 30–40 % patients develop NPS (e.g. anxiety, insomnia, distrust of others) 30–40 % patients present more severe NPS (e.g. aggression and depression) Almost 100 % patients present severe symptoms
About 50 % patients dependent on caregivers About 90 % of patients dependent on a caregiver
  1. NPS: neuropsychiatric symptoms