Table 1 Properties and distributions of ASIC subunits
From: Acid-sensing ion channels: potential therapeutic targets for neurologic diseases
ASIC subtype | pH sensitivity | Distribution |
|---|---|---|
ASIC1a | 5.8–6.8 | CNS and PNS |
ASIC1b | 6.1–6.2 | PNS |
ASIC2a | 4.5–4.9 | CNS and PNS |
ASIC2b | not applicable | CNS and PNS |
ASIC3 | 6.4–6.6 | PNS |
ASIC4 | not applicable | CNS and PNS |