Table 3 Regional differences in grey matter volume between individuals with AD and HC
From: Voxel-based meta-analysis of grey matter changes in Alzheimer’s disease
Region | Maximum | Cluster | Jackknife sensitivity analysis (combination of studies detecting the differences) | |||
|---|---|---|---|---|---|---|
MNI coordinates x y z | SDM value | P value | Number of voxels | Clusters breakdown (no. of voxels) | ||
Left parahippocampl gyrus, BA36 | −30,-10,-28 | −6.544 | ~0 | 3440 | Left parahippocampal gyrus (676) | 30 out of 30 |
Left insula (515) | ||||||
Left temporal gyrus (879) | ||||||
Left hippocampus (706) | ||||||
Left inferior frontal gyrus (450) | ||||||
Left rolandic operculum (214) | ||||||
Right fusiform gyrus | 34,-8,-30 | −6.257 | ~0 | 5838 | Right temporal gyrus (3300) | 29 out of 30 |
Right parahippocampal gyrus (813) | ||||||
Right hippocampus (521) | ||||||
Right rolandic operculum (447) | ||||||
Right insula (757) | ||||||
Left posterior cingulate gyrus, BA 23 | −8,-48,32 | −3.880 | ~0 | 1866 | Left /Right precuneus (1056) | 30 out of 30 |
Left/Right posterior cingulate gyrus (358) | ||||||
Left/Right median cingulate/paracingulate gyri (452) | ||||||
Right superior frontal gyrus, medial orbital, BA 11 | 4,34,-12 | −3.362 | 0.000474795 | 221 | Left/Right superior frontal gyrus, medial orbital (84) | 28 out of 30 |
Left /Right gyrus rectus (23) | ||||||
Left anterior cingulate/paracingulate gyri (18) | ||||||