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Figure 4 | Translational Neurodegeneration

Figure 4

From: Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease

Figure 4

ALDH1A7 is highly homologous to ALDH1A1 in the mouse genome. (A) Diagrams depict the genomic structures of human ALDH1A1 (hALDH1A1) and mouse Aldh1a1 (mAldh1a1) and Aldh1a7 (mAldh1a7). Arrows point to the direction of transcription. (B) Table shows the percentage of identical amino acids shared between hALDH1A1, mALDH1A1, and mALDH1A7 proteins. (C) Western blot shows the residual proteins recognized by an ALDH1A1 antibody in both the midbrain (MB) and striatum of Aldh1a1–/– mice.

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Translational Neurodegeneration

ISSN: 2047-9158

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