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Table 1 Intranuclear inclusion counts

From: Intranuclear inclusions in a fragile X mosaic male

 

Frontal Cortex

Temporal Cortex

Cerebellum

Hippocampus--CA1

Hippocampus--DG

(Gray Matter)

(Gray Matter)

(Granule Cell Layer)

(Pyramidal Cell Layer)

(Granule Cell Layer)

 

Neurons

Astroglia

Neurons

Astroglia

Neurons

Astroglia

Neurons

Astroglia

Neurons

Astroglia

Case 1

7 of 206

19 of 421

4 of 189

25 of 311

30 of 1424

42 of 644

5 of 122

11 of 245

15 of 532

8 of 126

mean

3.40%

4.51%

2.12%

8.03%

2.10%

6.52%

4.09%

4.49%

2.82%

6.35%

Greco et al., 2006 [8]

4.4%

16.7%

na

na

na

na

10.1%

10.3%

2.1%

26.6%

Tassone et al., 2012 [34]

5.6%

4.24%

11.59%

9.85%

na

na

6.59%

8.84%

4.66%

11.56%

Hunsaker et al., 2011

0.4%

0.93%

na

na

na

na

na

na

0.68%

1.34%

  1. na Data not available.
  2. This table shows the number of neurons and astroglia containing intranuclear inclusions in this Case as a function of the number of cells counted. Also included are intranuclear inclusion prevalence data from male FXTAS cases reported by [8], female FXTAS cases reported by [37], and male FXS reported by [26] to provide context for where along the fragile X associated disorder spectrum this size mosaic case fits.