Figure 8
From: Erythropoietin prevents PC12 cells from beta-amyloid-induced apoptosis via PI3K⁄Akt pathway
Involvement of PI3K/Akt in the effects of Epo on the Abeta (25-35) - decreased cell viability determined by MTT. We treated the cells with PI3K inhibitor LY294002 and found the protective effects of Epo on the Abeta(25-35)-decreased cell viability were diminished (P < 0.05). Three independent experiments were performed in duplicate (*: P < 0.05 vs. the controls and #: P < 0.05 vs. 20 μM Abeta(25-35)).