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Figure 2 | Translational Neurodegeneration

Figure 2

From: Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation

Figure 2

Macroautophagy marker immunohistochemistry in PD. (A) ATG8/LC3-immunopositive cells were observed in both end-stage sporadic PD as well as in cases with A53T mutations where α-synuclein accumulations are found in the cortex, and were not observed in earlier PD stages or in controls (B) where there is an absence of cortical α-synuclein accumulation. In isolated Lewy bodies identified with α-synuclein antibodies (C, D), there was no ATG8/LC3immunoreactivity.

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Translational Neurodegeneration

ISSN: 2047-9158

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