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Table 1 Proposed gradation of risk for AD in asymptomatic persons

From: Prevention strategies for Alzheimer’s disease

•  Basic risk (age)

•  Vascular risk factors

•  Family history of AD in first degree relatives but of late onset (>75)

•  Family history of younger onset (65–75)

•  Family history and ApoE4 +

•  Biomarker + (ex. PET amyloid positive scan)

•  Autosomal dominant mutation carrier