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Table 3 Correlations of cortical thickness signature scores at baseline with clinical parameters at baseline and at 4-year follow-up in iRBD

From: Longitudinal evolution of cortical thickness signature reflecting Lewy body dementia in isolated REM sleep behavior disorder: a prospective cohort study

 

DLB-pattern

AD-pattern

Mean cortical thickness

Baseline

4-year progression

Baseline

4-year progression

Baseline

4-year progression

Correlation coefficient

P

Correlation coefficient

P

Correlation coefficient

P

Correlation coefficient

P

Correlation coefficient

P

Correlation coefficient

P

B-SIT

− 0.14

0.40

N.A

N.A

− 0.19

0.24

N.A

N.A

0.039

0.21

N.A

N.A

Cognition*

− 0.017

0.91

0.026

0.92

0.23

0.13

0.19

0.44

− 0.086

0.57

0.054

0.83

MDS-UPDRS part I 

0.14

0.36

− 0.28

0.28

0.27

0.069

− 0.19

0.44

− 0.11

0.46

− 0.31

0.20

MDS-UPDRS part II 

0.13

0.39

− 0.11

0.67

0.27

0.065

0.15

0.55

− 0.11

0.47

− 0.19

0.45

MDS-UPDRS part III 

0.08

0.56

− 0.044

0.25

0.16

0.29

0.33

0.17

− 0.18

0.23

− 0.26

0.28

Digit span test

− 0.32

0.033

0.29

0.61

− 0.036

0.82

0.064

0.81

− 0.039

0.80

0.10

0.70

TMT-A

− 0.21

0.21

0.13

0.067

− 0.12

0.47

0.057

0.83

− 0.084

0.61

0.33

0.21

CWST

0.31

0.075

− 0.43

0.31

− 0.11

0.54

− 0.41

0.12

0.11

0.54

− 0.13

0.62

BNT

0.042

0.79

− 0.23

0.37

− 0.019

0.90

− 0.22

0.37

− 0.26

0.082

− 0.088

0.72

RCFT

− 0.067

0.68

− 0.22

0.035

0.17

0.26

− 0.34

0.17

− 0.22

0.16

− 0.0062

0.98

SVLTi

0.073

0.65

− 0.46

0.018

0.25

0.097

− 0.46

0.048

0.080

0.60

− 0.085

0.73

SVLTd

0.061

0.70

− 0.51

0.068

0.12

0.42

− 0.60

0.007

0.16

0.29

− 0.44

0.057

SVLTr

− 0.073

0.64

− 0.41

0.54

0.18

0.25

− 0.24

0.33

− 0.17

0.27

0.23

0.35

COWAT

0.067

0.68

− 0.16

0.54

0.0076

0.96

− 0.19

0.49

0.022

0.89

0.11

0.69

TMT-B

0.25

0.13

− 0.002

0.99

0.10

0.58

0.32

0.24

− 0.052

0.78

0.29

0.29

  1. Age and sex were included as cofactors for correlation analysis between cortical thickness signature scores (DLB-pattern, AD-pattern and mean cortical thickness) and clinical variables (SIT, MDS-UPDRS part I, II and III). Age, sex and education year were included as cofactors in the correlation analysis between cortical signature scores with cognitive profiles (Cognition* from MDS-UPDRS part I subscore and scores from neuropsychological tests)
  2. The significant values (P < 0.05) are shown in bold
  3. B-SIT Brief smell identification test, BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CWST Korean Color Word Stroop Test, SIT Smell identification test, MDS-UPDRS Movement Disorders Society-Unified Parkinson Disease Rating Scale, TMT Trail Making Test, RCFT Rey Complex Figure Test copy, SVLTi SVLTd, SVLTr: immediate recall, delayed recall and recognition in Seoul Verbal Learning Test, respectively. N.A. Not Applicable
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Translational Neurodegeneration

ISSN: 2047-9158

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