Table 5 Clinicopathological features of predominant argyrophilic grain disease (AGD) cases
|  | Predominant AGD cases (n = 39) | Control cases (n = 589) | Age-, sex-, and comorbid pathology-matched predominant AGD cases (n = 37) | Age-, sex-, and comorbid pathology-matched control cases (n = 37) |
|---|---|---|---|---|
Age, mean ± SD, years | 72.5 ± 12.1**** | 59.3 ± 12.0 | 71.7 ± 2.0 | 70.9 ± 2.0 |
Sex (male/female) | 23/16 | 417/172 | 22/15 | 23/14 |
BMI, mean ± SD | 21.0 ± 3.8 | 21.9 ± 4.7 | 21.0 ± 3.9 | 21.5 ± 4.7 |
Cause of death | ||||
 Suicide, n (%) | 16 (41.0) | 183 (31.1) | 15 (40.5)# | 7 (18.9) |
 Homicide, n (%) | 0 (0.0) | 11 (1.9) | 0 (0.0) | 0 (0.0) |
 Accidental death, n (%) | 18 (46.2) | 216 (36.7) | 17 (46.0) | 16 (43.2) |
 Natural causes, n (%) | 5 (12.8)# | 173 (29.4) | 5 (13.5)# | 14 (37.8) |
Past medical history | ||||
 Dementia, n (%) | 4 (10.3)#### | 2 (0.3) | 3 (8.1) | 0 (0.0) |
 Medical history of psychiatric disease, n (%) | 7 (18.0) | 110 (18.7) | 7 (18.9) | 5 (13.5) |
Pathological findings | ||||
 Brain weight, mean ± SD, g | 1332.5 ± 151.4* | 1395.9 ± 148.0 | 1338.3 ± 152.5 | 1377.9 ± 119.1 |
 Heart weight, mean ± SD, g | 368.5 ± 66.7 | 384.8 ± 100.5 | 370.2 ± 67.4 | 397.8 ± 85.2 |
 Braak AD tau stage, mean ± SD | 1.8 ± 0.5**** | 1.0 ± 0.8 | 1.8 ± 0.5 | 1.8 ± 0.4 |
 Thal amyloid beta phase, mean ± SD | 0.4 ± 0.7 | 0.3 ± 0.6 | 0.4 ± 0.7 | 0.3 ± 0.6 |
 CERAD amyloid beta stage, mean ± SD | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.2 ± 0.4 |