Fig. 3
From: α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies
Potential strain typing by RT-QuIC. A schematic illustration indicating the possible outcomes of RT-QuIC to distinguish a classical signal (in blue) from various conditions. All-or-none response (a), different lag-phases with the same IMax (b), different IMax with the same lag-phase (c), same lag-phase and IMax, but with steeper aggregation phase (different areas under the curve) (d), and different lag-phases and IMax (e), can be applied to distinguish between different seeding efficiencies