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Fig. 5 | Translational Neurodegeneration

Fig. 5

From: Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial

Fig. 5

Structural magnetic resonance imaging analysis. a Increased cortical thickness (red-yellow) in the study group (P < 0.05) in the inferior parietal, lateral occipital and middle frontal and paracentral cortical regions based on the illustration of FreeSurfer's Qdec application. b Segmentation maps of the hippocampal subfields displayed on the sagittal (top), axial (middle), and coronal (bottom) planes. c Hippocampal subfield measurements showing increased volumes in the study group (P < 0.05) in the left mean hippocampal (upper left) and left hippocampal molecular layer (lower left) based on the FreeSurfer's Qdec application. Other sub-anatomic hippocampal regions iii) including left CA1 body (upper right) and iv) left whole hippocampal body (lower right) were not significant but near to a statistically significant level (P > 0.05)

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