Table 1 Demographic data, medication, target coordinates, and stimulation parameters
Patient | Age/Sex | Baseline | Medication (daily dose) | Target coordinatesa (x,y,z) | Contactsb | Stimulation setting | |
|---|---|---|---|---|---|---|---|
MMSE | ADAS-Cog | ||||||
sub_1 | 61/F | 5 | 64 | Donepezil (5 mg) | − 28.5, − 5.0, − 7.4 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.0 V |
26.9, − 7.3, − 7.6 | |||||||
sub_2 | 67/M | 9 | 40 | Donepezil (10 mg) | − 27.2, − 4.7, − 7.0 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.5 V |
Memantine (20 mg) | 26.0, − 5.2, − 9.0 | ||||||
Aniracetam (0.6 g) | |||||||
sub_3 | 66/M | 8 | 37 | Donepezil (10 mg) | − 24.6, − 7.1, − 8.7 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 3.0 V |
Memantine (20 mg) | 25.6, − 6.2, − 7.7 | ||||||
sub_4 | 78/M | 16 | 19 | / | − 26.3, − 6.1, − 10.1 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.5 V |
25.9, − 5.5, − 9.5 | |||||||
sub_5 | 67/F | 7 | 62 | Donepezil (5 mg) | − 23.8, − 9.2, − 5.2 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 3.0 V |
Memantine (2.5 mg) | 22.5, − 10.1, − 6.4 | ||||||
sub_6 | 70/M | 4 | 58 | Donepezil (10 mg) | − 25.2, − 6.0, − 6.5 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.5 V |
24.1, − 6.7, − 5.5 | |||||||
sub_7 | 59/F | 4 | 63 | Donepezil (10 mg) | − 24.8, − 6.3, − 7.6 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.5 V |
Huperzine A (0.1 mg) | 26.1, − 6.1, − 5.4 | ||||||
Oxiracetam (0.4 g) | |||||||
sub_8 | 65/M | 2 | 60 | Donepezil (10 mg) | − 20.7, − 7.8, − 7.4 | C + 2 − /C + 6 − | 20 Hz, 90 μs, 2.5 V |
Memantine (5 mg) | 25.1, − 7.2, − 7.8 | ||||||