From: ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein
Variant
Half-life (h)
AUC
Fast phase
Slow phase
[125I]I-OX265-F(ab′)2-Bapi
0.50 (0.41–0.59)
10.78 (8.02–14.15)
77.34 (69.85–84.84)
[124I]I-OX2676-F(ab′)2-Bapi
1.22 (0–2.41)
9.17 (7.13–25.96)
82.85 (73.09–92.62)