Fig. 4
From: Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis
Associations between cognition-related genera and brain structure in the GNHS. a Linear regression was used to estimate associations between cognition-related genera and brain structure. The β-coefficients indicate the corresponding changes in standardized volumes of different brain areas for per 1-standardize unit (in SD unit) increase of the bacterial relative abundance. False discovery rate (FDR) was calculated using the Benjamini–Hochberg method. *FDR < 0.05. b β-Value maps of linear mixed-effect model show a positive association between the relative abundance of Odoribacter and the right hippocampal volume (one-way T test, FDR < 0.05, voxel > 10). GNHS Guangzhou Nutrition and Health Study, GM grey matter, WM white matter, CSF cerebrospinal fluid, L left, R right, Frontal_Sup superior frontal gyrus, dorsolateral, Frontal_Mid middle frontal gyrus, Frontal_Inf_Oper inferior frontal gyrus, opercular part, Frontal_Inf_Tri inferior frontal gyrus, triangular part, Frontal_Inf_Orb inferior frontal gyrus, orbital part