Table 2 Results of burden analysis at the KIF1A gene level in different cohorts
From: Association of variants in the KIF1A gene with amyotrophic lateral sclerosis
| Â | Entire gene | C-terminal cargo-binding region | ||||||
|---|---|---|---|---|---|---|---|---|
Cohort | AC (patients) | AC (controls) | P value | OR [95% CI] | AC (patients) | AC (controls) | P value | OR [95% CI] |
This study | 10 (941) | 33 (6708) | 0.036* | 2.17 [1.07–4.40] | 9 (941) | 18 (6708) | 0.004* | 3.58 [1.60–7.98] |
Project Mine | 19 (4366) | 2 (1832) | 0.053 | 4.00 [0.93–17.15] | 17 (4366) | 2 (1832) | 0.079 | 3.57 [0.83–15.47] |