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Fig. 4 | Translational Neurodegeneration

Fig. 4

From: Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

Fig. 4

RT-QuIC detection of α-syn seeding activity in CSF samples of patients with PD and non-PD. a The average of relative ThT fluorescence from four replicate readings obtained from CSF of each individual cases with PD (n = 24) and non-PD (n = 19) at 80 h. Bars show the average ± SD for each group. The dashed line shows the fluorescence threshold for a positive result. b Traces represent the average percentage of ThT fluorescence readings from positive 22/24 CSF samples from patients with PD and 1/19 non-PD . The means (thick lines) with SD (thin lines) of those averages are shown as a function of RT-QuIC reaction time

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Translational Neurodegeneration

ISSN: 2047-9158

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