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Fig. 4 | Translational Neurodegeneration

Fig. 4

From: Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy

Fig. 4

Bulk tissue level of pS129 αS in spinal cord is not affected by tau expression in TgA53T mice at 70 dpi. a Representative immunoblots of total αS (a) and pS129 αS (b) in spinal cord of 70-dpi mice. c, d Quantitation of immunoblots shown in a and b. Total αS (c), and pS129 αS normalized to total αS (d) were not different between TgA53T and TgA53T/mTau−/− mice in 70-dpi spinal cord lysates (t test, P = 0.1575 and P = 0.7993, respectively). All quantified bands were normalized to the respective ponceau S total protein. Abbreviations: ponceau S, ponc; arbitrary units, A.U.; n = 4 animals/genotype; error bars represent mean ± SEM

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