Fig. 3
From: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases
ALSFRS-R functional decline reported by phase II studies on TUDCA in ALS. The mean reported decline is plotted for the study on TUDCA alone (blue) [89] and for TUDCA and NaPB study (red) [90]. Solid lines indicate the active groups; dashed lines represent the control groups. The table reports means (± SD) for baseline and end-of-study measures [89, 90]. Abbreviations: ALSFRS-R, Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised; NaPB, sodium phenylbutyrate; TUDCA, tauroursodeoxycholic acid